MicroGAM – Milk and microbiota dysblasis in malnourished children

Malnutrition remains a global challenge and is responsible for over 40% of child mortality. Despite improvements in the quality of nutrition, treatment outcomes are still lower than expected. This is probably since poor intestinal function and intestinal microbiota dysbiosis have a great influence on the adsorption and utilization of nutrition.

By: Grith Mortensen

The purpose of the MicroGAM project is to investigate the effect of milk components on the re-establishment of the intestinal microbiota in malnourished children. Various milk components will be examined. Stool samples from two Ugandan children's cohorts with severe and moderate malnutrition who have already been enrolled in two already funded projects, MAGMAM and LARISAM, will be analyzed. The samples will be analyzed and compared with relevant control groups. In addition, it is investigated how re-establishment of the intestinal microbiota is associated with increased growth. All in all, the plan for the project is to clarify whether - and how - milk can contribute to a better intestinal microbiota in malnourished children and thus promote health and growth.

Project: January 2019 - December 2021

Budget: 2.368.000 DKK

Financing: Danish Research Foundation, Chinese Scholarship Council (CSC), In-kind from University of Copenhagen

Project manager: Benedikte Grenov

Institution: Department of Nutrition, Exercise and Sports, University of Copenhagen

Participants: Department of Nutrition, Exercise and Sports University of Copenhagen, Department of Food Science, University of Copenhagen, and Department of Paediatrics and Child Health, Markere University, Kampala, Uganda