CutDM hypo-energetic study: 

Optimizing diabetes reducing diet carbohydrate and energy

By: Grith Mortensen

The aim of the project is to investigate in a clinical setting the ability of a controlled low carbohydrate hypo-energetic diet enriched by dairy protein to improve carbohydrate and lipid metabolism in prediabetes and diabetic patients compared with the recommended diabetic diet. A focus will be on palatability of meals. The study will highlight pathophysiological mechanisms of the disease that can be addressed by the experimental diet, including beta-cell function, insulin resistance, and disturbed lipid metabolism. It is also likely that the experimental diet will improve diurnal blood pressure and the heart rate variability. The results are likely to show an effective non-pharmacologic treatment of type 2 diabetes.

Project period: January 2018 - December 2021

Budget: 6.208.000 DKK

Financing: Milk Levy Fund, Bispebjerg Hospital, Novo Nordisk, BFH Forskningsfond

Project manager: Steen Bendix Haugaard

Institutions: Endocrinology Department I, Copenhagen University Hospital - Bispebjerg

Participants: Endocrinology Department, Copenhagen University Hospital – Bispebjerg, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Endocrinology Department, Hvidovre Hospital, University of Copenhagen, and Department of Clinical Medicine, Aarhus University