CutDM hypo-energetic study:
Optimizing diabetes reducing diet carbohydrate and energy
By: Grith Mortensen
The aim of the project is to investigate in a clinical setting the ability of a controlled low carbohydrate hypo-energetic diet enriched by dairy protein to improve carbohydrate and lipid metabolism in prediabetes and diabetic patients compared with the recommended diabetic diet. A focus will be on palatability of meals. The study will highlight pathophysiological mechanisms of the disease that can be addressed by the experimental diet, including beta-cell function, insulin resistance, and disturbed lipid metabolism. It is also likely that the experimental diet will improve diurnal blood pressure and the heart rate variability. The results are likely to show an effective non-pharmacologic treatment of type 2 diabetes.
Project period: January 2018 - December 2021
Budget: 6.208.000 DKK
Financing: Milk Levy Fund, Bispebjerg Hospital, Novo Nordisk, BFH Forskningsfond
Project manager: Steen Bendix Haugaard
Institutions: Endocrinology Department I, Copenhagen University Hospital - Bispebjerg
Participants: Endocrinology Department, Copenhagen University Hospital – Bispebjerg, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Endocrinology Department, Hvidovre Hospital, University of Copenhagen, and Department of Clinical Medicine, Aarhus University
Email: gmo@lf.dk